986
Index
Cirrhosis, 123 
11-ds-retinaldehyde, 908 
13-«s-retinoic acid, 907 
13-ds-retinoic acid (isotretinoin), 907 
Citrate, 241
Citrate dehydrogenase, 336 
Citrate synthase, 241 
Citrate-phosphate-dextrose, 655 
Citric acid cycle, 
se e
Tricarboxylic acid 
(TCA) cycle 
Citrovorum factor, 617 
Citrulline, 26, 332, 342 
CK, 471,472 
CK-2, 472 
C282Y and H63D 
CKMB serum marker, 126 
Cl~ transport, 221 
Class (isotype) switching, 826 
Class I introns, 571 
Class II introns, 571 
Class I MHC, 808 
Class II MHC, 808
Classical “cascade” or “waterfall” model 
for coagulation, 841 
Classical pathway, 808 
Clathrin, 186,437
Cleavage of fructose 1,
6
.bisphosphate, 229 
CLIA (chemiluminescence immunoassay), 
124, 130
vs. EIA and ELISA, 130 
Clofibrate, 449 
Chloramphenicol, 585 
Clot dissolution—fibrinolysis, 841 
Clotting, 851 
CN~ derivative, 672 
CO production in mammals, 690 
CO
2
transport, 655 
C0
2
loss in alveolus, 
8 
C0
2
transport from the tissues to the 
blood, 7
Coagulation factor 
deficiency, 863 
measurements, 863 
Coagulation factor deficiency, 863 
Coagulation factor measurements, 863 
Coated pit, 437 
deficiency, 351
Cobalamin (vitamin B]2), 354, 918 
Cobalophilins, 918
Cobalophilins (R-proteins; R-binders), 919 
Cobalt, 892
Cobalt-containing compounds, 102
Cobamide coenzyme, 107
Cockayne’s syndrome, 559
Coconut oil, 218
Coding strand, 566
Codons, 267, 564
Coenzyme A (CoA, CoASH), 107
Coenzyme Q (CoQ, ubiquinone), 107 
Coenzyme Q cytochrome c reductase, 
251,254
Coenzymes, 85, 106 
Cofactor proteins, 842 
Cofactor, 85, 106 
Colchicine, 483, 632 
C o lch icu m au tu m n ale,
483 
Colestipol, 449, 450 
Colipase, 127, 202 
Colipase deficiency, 217 
Collagen, 23, 54, 173, 214, 331, 585 
biosynthesis, 585 
diseases
mechanisms, 586 
polymerized fibrillar, 176 
polypeptides
transcription and translation of, 586 
synthesis of, 245 
turnover, 179
turnover and tissue repair, 178 
Collagen biosynthesis 
disorders, 585 
Collagen fibrils 
formation, 589 
Collagen molecules 
ordered aggregation of
formation of collagen fibrils, 589 
Collagen polypeptides, 586 
Collagenase, 178, 179 
Collagens, 154
Colligative properties of water, 3 
Colloid, 769 
coupling reaction, 771 
Colloid goiter, 774 
Colonic bacteria, 202 
Colonic cancer, 149 
Colony-forming unit erythroid, 656 
Colorectal adenocaricnoma, 600 
Colorectal cancer, 612 
Colorectal, other carcinomas, 612 
Columnar epithelial cells, 208 
Columnar mucosal cells, 218 
Committed step, 109
Common tests of hemostatic function, 865 
Compartment disorders, 581 
I-cell disease, 581 
mucolipidosis, 581 
Competitive inhibition, 92, 96 
Complement, 808, 827 
Complement receptor, 830 
Complementary polydeoxynucleotide 
strands, 525 
Complex, 312 
Complex I, 251 
assembly of, 267 
Complex II, 253 
Complex III, 254
Complex IV, 255, 257 
Components of the electron transport 
chain, 251
Components of the hemostatic 
system, 843
Components of the immune 
system, 808
Compulsive disorders, 535 
Concanavalin A, 194 
Concentration gradient-dependent 
facilitated transport, 225 
Concept of AG, 71 
Condensation of acetyl-CoA with 
oxaloacetate to form citrate, 241 
Cone cells, 909 
Configuration, 51 
Conformation, 51 
Conformational hypothesis, 258 
Congenital adrenal hyperplasia, 757, 758 
Congenital atransferrinemia, 681 
Congenital deficiency, 216 
Congenital erythropoietic porphyria, 685, 
687, 689
Congenital hypothyroidism, 778 
Congenital methemoglobinemias, 
6 6 8 
Conjugation, 526, 547 
Conn’s syndrome, 759 
Conradi-Hunermann syndrome, 421 
Conservation of energy, 257 
Constitutive synthesis, 594 
Contact inhibition of cell growth, 161 
Contact phase, 855 
Contact Phase of the 
In Vitro,
857 
Contact phase proteinases 
inhibitors of, 859 
Contact system (phase), 857 
Contemporary model for the procoagulant 
subsystem, 842 
Contractile properties, 462 
Contractile systems 
muscle, 453 
nonmuscle, 453 
Contracting muscle, 233 
Contrast, 465 
Control of food intake 
appetite hunger, 497 
Control of glycogen phosphorylase, 288 
Control of glycogen synthase, 290 
Convergent evolution, 652 
Conversion of fructose 1,
6
-bisphosphate to 
fructose 
6
-phosphate, 280 
Conversion of oxaloacetate to 
phosphoenolpyruvate, 280 
Conversion of succinyl-CoA to 
succinate, 243 
Cooley’s anemia, 682 
Coordinate regulation of iron uptake and 
storage in non-erythroid cells, 679