Lipids li: Phospholipids, Glycosphingolipids, and Cholesterol
A partial pathway for the conversion of lanosterol to cholesterol. The complete process consists of 19 steps. The
double bond can be reduced by 3/1-hydroxylsteroid- A24-reductase at several steps along the pathway
(indicated by 1), and deficiency of this enzyme leads to accumulation of desmosterol. Deficiency of enzyme 2 and
enzyme 3 results in CDPX2 and SLO syndromes, respectively (see text).